Skin SNAP-8

Premium SNAP-8 for skin signaling research

SNAP-8 — an acetylated octapeptide — studied as a SNAP-25/SNARE-complex cosmetic research fragment.

SNAP-8

Research overview

SNAP-8 is a synthetic 8-amino-acid peptide sold as a cosmetic ingredient by Lipotec (owned by Lubrizol, which is owned by Berkshire Hathaway). It was designed as an extended version of Argireline, with the same basic idea but two extra amino acids added. Both are modeled on a small piece of SNAP-25 — a protein that nerve endings use to release chemicals onto muscles. The theory: if this peptide fills in for part of SNAP-25, it partially disrupts that release, producing slightly weaker muscle contractions and shallower expression lines over time. At 1,075 Da (daltons), it is a relatively large cosmetic peptide. That size creates a delivery problem: the outer skin barrier (the stratum corneum) acts as a wall, and molecules over 500 Da generally have trouble crossing it. SNAP-8 is more than twice that size. Most research now focuses on how to push it past that barrier (dissolving microneedles, liposomes), not on the peptide itself. It is not approved as a drug anywhere in the world. It is only regulated as a cosmetic ingredient.

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Details

Strength:10mg
Form:Lyophilized research material
Testing:Third-party tested
Documentation:COA available
02.

Handling

Keep lyophilized research material sealed, protected from light, and handled with standard laboratory controls. Follow internal SOPs for storage, reconstitution, labeling and disposal.

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Regulation

Not approved as a therapeutic drug for any human indication. Permitted in the United States as a cosmetic ingredient under 21 CFR Part 701 when used in finished cosmetic products; cosmetic ingredient safety is the responsibility of the manufacturer, not FDA pre-market approval.

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Molecules

SNAP-8 is an acetylated octapeptide related to the SNAP-25 SNARE-complex protein. PubChem indexes SNAP-8 at CID 86080331 with formula C41H70N16O16S, molecular weight 1075.16 g/mol, and CAS 868844-74-0.

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Testing

We display batch-level certificates of analysis (mass spec, HPLC purity) for all research-grade material.

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Lyophilized peptides manufactured in GMP-certified facilities. No fillers, no shortcuts.

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Third-Party Tested

We display batch-level certificates of analysis (mass spec, HPLC purity) for all research-grade material.

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IMPORTANT: All products sold by Premium Peptides are intended for laboratory research only. They are not intended for human consumption, medical use, or as substitutes for prescription medications. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.