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Details
Strength:5mg
Form:Lyophilized research material
Testing:Third-party tested
Documentation:COA available
Sermorelin — the GHRH(1-29) research peptide — used to study pulsatile growth-hormone signaling.
Sermorelin is a synthetic 29-amino-acid peptide identical to the first 29 amino acids of the body's natural growth-hormone-releasing hormone (GHRH) — the signal that normally tells the pituitary gland to release growth hormone. The 29-amino-acid version is the shortest piece of GHRH that still works at full strength. One small modification makes it more stable in the bloodstream. Because it clears from the blood in only about 5 to 10 minutes, each dose causes a brief spike of growth hormone and then disappears before the body's natural braking systems are overwhelmed. This preserves the pulsatile rhythm of GH release. It was marketed as Geref (Serono) from 1990 to 2008. CJC-1295 and tesamorelin were both built from the same backbone.
Keep lyophilized research material sealed, protected from light, and handled with standard laboratory controls. Follow internal SOPs for storage, reconstitution, labeling and disposal.
Historically FDA-approved. Geref (sermorelin acetate, Serono) received FDA diagnostic approval in 1990 and therapeutic approval in 1997 for idiopathic pediatric growth hormone deficiency. Commercial production was discontinued in 2008 for manufacturing reasons, not safety or efficacy. No FDA-approved sermorelin product is currently marketed. The molecule remains available in the United States only as a compounded preparation (503A) or as a research chemical.
Sermorelin is a 29-amino-acid GHRH(1-29) analog with C-terminal amidation. PubChem indexes it at CID 16132413 with formula C149H246N44O42S and molecular weight 3357.9 g/mol.
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Lyophilized peptides manufactured in GMP-certified facilities. No fillers, no shortcuts.
We display batch-level certificates of analysis (mass spec, HPLC purity) for all research-grade material.
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