PT-141 — bremelanotide, a melanocortin receptor agonist — studied in central signaling pathways.
PT-141 (bremelanotide) is a lab-made 7-amino-acid peptide. It was developed out of a bigger molecule called Melanotan II. Palatin Technologies brought it through the FDA, and it was approved in 2019 as Vyleesi for women with low sexual desire. Unlike Viagra-type drugs that work on blood flow, PT-141 works in the brain.
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Approved (2019, for premenopausal HSDD in women, brand name Vyleesi)
PT-141 is bremelanotide, a cyclic melanocortin receptor agonist derived from Melanotan II research. PubChem indexes bremelanotide at CID 9941379 with formula C50H68N14O10 and molecular weight 1025.2 g/mol.
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