Longevity Epitalon

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Epitalon — a synthetic AEDG tetrapeptide — studied in aging, pineal, and telomere-related research models.

Epitalon

Research overview

Epitalon is a lab-made peptide — a chain of just four amino acids (the building blocks of proteins): alanine, glutamic acid, aspartic acid, and glycine, abbreviated AEDG. Vladimir Khavinson's team in St. Petersburg made it in the early 1990s. They built it to be the active piece of an older cow-pineal-gland extract called Epithalamin that was used in Soviet-era aging medicine. The Khavinson group later reported (in 2017) that trace amounts of this same four-peptide chain also appear naturally in the human pineal gland, so they reclassified it as something the body already makes rather than a purely synthetic drug. It's not an approved drug anywhere in the world, and in the U.S. it's only sold as a research chemical for lab studies.

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Details

Strength:10mg
Form:Lyophilized research material
Testing:Third-party tested
Documentation:COA available
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Handling

Keep lyophilized research material sealed, protected from light, and handled with standard laboratory controls. Follow internal SOPs for storage, reconstitution, labeling and disposal.

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Regulation

Not approved for any indication. Has never been filed with FDA. Sold in the United States only as a research chemical for in-vitro and animal study. No IND on file in the Drugs@FDA registry as of the April 15, 2026 503A Categories Update; Epitalon is not listed in FDA 503A Category 1.

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Molecules

Epitalon is the AEDG tetrapeptide, Ala-Glu-Asp-Gly. PubChem indexes it at CID 219042 with formula C14H22N4O9, molecular weight 390.35 g/mol, and CAS 307297-39-8.

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Testing

We display batch-level certificates of analysis (mass spec, HPLC purity) for all research-grade material.

Why Premium Peptides?

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Premium Purity

Lyophilized peptides manufactured in GMP-certified facilities. No fillers, no shortcuts.

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Third-Party Tested

We display batch-level certificates of analysis (mass spec, HPLC purity) for all research-grade material.

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Free Shipping

Discreet, temperature-controlled shipping included on every order. No hidden fees.

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Fast Fulfillment

Orders processed within 24 hours. Most shipments arrive in 3–5 business days.

IMPORTANT: All products sold by Premium Peptides are intended for laboratory research only. They are not intended for human consumption, medical use, or as substitutes for prescription medications. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.