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Details
Strength:5mg
Form:Lyophilized research material
Testing:Third-party tested
Documentation:COA available
AOD-9604 — a cyclic hGH(177-191) fragment — studied in metabolic and lipolysis research.
AOD-9604 is a lab-made chain of 16 amino acids (the building blocks of proteins). It copies the tail end of human growth hormone — the piece scientists think is responsible for burning fat. One small change was added to make it more stable. A chemical bond folds the chain into a loop that mimics the shape of that piece inside the real hormone. Researchers at Monash University in Australia designed it in the 1990s. A company called Metabolic Pharmaceuticals then developed it. Unlike real growth hormone, AOD-9604 does not attach to the main growth-hormone receiver. It does not raise the usual blood growth signal. It does not make muscles or bones grow. Those effects were deliberately designed out. After the big 2007 weight-loss trial failed, the company relabeled it as a food ingredient instead of a drug. It has never been FDA-approved for any medical use.
Keep lyophilized research material sealed, protected from light, and handled with standard laboratory controls. Follow internal SOPs for storage, reconstitution, labeling and disposal.
Not approved for human use. Phase 2b obesity clinical development was terminated by Metabolic Pharmaceuticals / Calzada in 2007 after the 24-week Phase 2b trial failed its primary weight-loss endpoint. AOD-9604 was subsequently repositioned as a nutraceutical ingredient and granted self-affirmed GRAS status for food use (Moré et al. 2014); the FDA has not issued an independent GRAS no-objection letter, and no NDA or BLA is open or pending. The April 15, 2026 FDA 503A Bulk Drug Substances Categories Update does not list AOD-9604 as an eligible substance for compounding in human drug products.
AOD-9604 is a cyclic hGH fragment with a Cys-Cys disulfide constraint. PubChem indexes it at CID 71300630 with formula C78H123N23O23S2, molecular weight 1815.1 g/mol, and CAS 221231-10-3.
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Lyophilized peptides manufactured in GMP-certified facilities. No fillers, no shortcuts.
We display batch-level certificates of analysis (mass spec, HPLC purity) for all research-grade material.
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